Sapient is a fast-growing early-stage biotech company headquartered in San Diego, CA. Our focus is on delivering multi-omics services to accelerate drug development and transform personalized medicine. Combining state-of-the-art mass spectrometry technology with advanced biocomputational services and multifaceted human health data, we enable biomarker discovery at unprecedented speed and scale to provide a deeper understanding of human biology and effectively align biological targets, patients, and drug therapies. We are a highly collaborative team of passionate scientists, clinicians, and engineers with expertise in various disciplines, committed to making innovations with scientific rigor. Ultimately, our platform technology enhances the precision and efficacy of treatments, touching and enhancing countless lives.
We are seeking a Proteomics Scientist to join our dynamic and growing company.
Role and Responsibilities:
- Independently design, evaluate and implement bottom-up and top-down methods for targeted and discovery-based protein measurement in biosamples using DDA and DIA LC-MS workflows.
- Independently deploy non-mass spectrometry-based methodologies for protein enrichment and quantitation including immunoprecipitation and PTM enrichment.
- Ensure data quality through implementation of data monitoring, QC metrics, standardized operating procedures, and formal staff training.
- Maintain LC-MS instrumentation, write standard operating procedures for new methods, and train others on new proteomics protocols for commercial deployment.
- Implement laboratory automation for sample preparation and data analysis pipelines.
- Able to perform and communicate within a collaborative environment with an emphasis on data quality, integrity, and adherence to project deadlines.
Requirements:
- Must have a PhD in Chemistry, chemical engineering, bioengineering, biochemistry, biology, or related scientific field
- A minimum of 5 years postdoctoral and/or professional experience working in proteomics with a focus on, but not limited to, mass-spectrometry-based methods
- Must demonstrate leadership capabilities including coaching and mentoring of junior scientists
- Ability to work in a fast paced client focused environment with a focus on detail and follow up with stakeholders