About GenScript
GenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. Founded in 2002, GenScript has an established global presence across North America, Europe, the Greater China, and Asia Pacific. GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.
GenScript is committed to striving towards its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology
About GenScript ProBio
GenScript ProBio is the subsidiary of GenScript Biotech Corporation, proactively providing end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy (CGT), vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers. GenScript ProBio's total cell and gene therapy solution covers CMC of plasmid and virus for IND filing as well as clinical manufacturing and commercial manufacturing. In terms of plasmid service, GenScript ProBio supports the most clinical approvals for CGT drugs including mRNA vaccines, CAR-T in China. It is also the first GMP manufacturing platform to provide in vitro transcription (IVT) template linearized plasmids for mRNA vaccines and has supported several mRNA vaccine global enterprises to obtain clinical approvals. In terms of viral vector service, GenScript ProBio has a stable and high-yield viral vector platform.
Job Scope:
GenScript is looking for a highly motivated and scientifically rigorous Nanoparticle Formulation Scientist to join our RNA team. This position will focus on developing novel lipid nanoparticle formulations for RNA delivery.
Location: Redmond, WA
Responsibilities:
- Develop new lipid nanoparticle formulations by designing and optimizing (lipid or other polymers) nanoparticle formulation for mRNA, DNA, RNA, peptide delivery.
- Develop method for characterizing and evaluating physical characteristics, loading efficiency and stability of nano-formulations.
- Produce formulations for related RNA projects, supporting functional assays for in vitro evaluation.
- Maintain relationships with customers, participate in scientific meetings or customer meetings.
- Write study protocols, technical reports, and SOPs to support mRNA product development projects.
- Interact with IP counsel to assist with patent prosecution.
- Monitors supply inventory and identifies any products required.
- Maintains work area, equipment, department and all storage areas in a clean, neat and orderly manner.
- Perform other duties as needed.
Qualifications:
- Master or PhD's degree in pharmaceutical science, chemistry, biochemistry, chemical engineering or related field, Master is preferred
- Strong knowledge of lipid and polymeric nanoparticle delivery technologies
- >4 years of relevant experience in nucleic acid delivery with hands-on experience in lipid nanoparticle formulation and characterization
- Extensive experience with production and analytical characterization of nanoparticles
- Proficiency in all molecular biology techniques for mRNA and protein expression (RT-PCR, ELISA, Western blot, Flow-cytometry, etc) and RNA-related analytics (ribogreen, gel electrophoresis, capillary electrophoresis, etc).
- Works collaboratively with team members to support each other
- Excellent communication and problem-solving skills
- A sense of humility and an eagerness to continue to learn and contribute to a supportive team
GenScript USA Inc/GenScript ProBio USA Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.
GenScript USA Inc./GenScript ProBio USA Inc. maintains a drug-free workplace.